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nky-article_size2 fs14"></i>中</a> <a class="size1 size_max"><i class="iconfont nky-article_size3 fs14"></i>大</a> </div> </div> <div id="ddvpr3yjlwe" class="article fs16 lh28"> 日前，中国农科院<a target="_blank">作物科学研究所</a>万建民院士领衔的水稻功能基因组学创新研究组，在水稻粒宽与粒重调控机制研究中取得重要进展，揭示了控制水稻?？碛肓Ｖ毓丶騁W5通过调节油菜素内酯信号途径调控水稻籽粒发育的新机制，为水稻高产育种提供了重要的理论依据。<br /> 水稻粒型是决定籽粒重量进而影响水稻产量和品质的重要性状。GW5/qSW5为较早报道的控制水稻粒宽、粒重且效应较强的数量性状基因座，对培育优质高产水稻品种具有重要的应用价值。早在2008年，万建民带领科研人员将GW5/qSW5位点成功定位在同一重叠区间内，发现存在于宽粒品种中的1,212-bp缺失与粒宽性状关联。后经研究，万建民团队明确了位于该1,212-bp缺失区域上游一个编码钙调蛋白的基因，能够显著影响水稻?？?，是GW5/qSW5位点的候选基因（仍命名为GW5）。他们的进一步研究发现，GW5蛋白定位在细胞质膜上，并可与油菜素内酯信号途径中的一个关键激酶GSK2直接互作，抑制GSK2磷酸化下游两个转录因子BZR1和DLT活性，使得非磷酸化状态的BZR1与DLT积累并进入细胞核中，调控BR下游响应基因表达，进而调控水稻粒型等生长发育过程。<br /> 研究人员还发现，通过CRISPR技术将GW5基因敲除，可以增加其它不含1,212-bp缺失的水稻品种籽粒的粒宽和粒重，达到增产效果。 </div>  <div id="ddvpr3yjlwe" class="article_bottom_btns"> <div id="ddvpr3yjlwe" class="article_btn print fs12 pr" onclick="javascript:window.print()"><i class="iconfont nky-article_print fs24 pa-l"></i>打印本页</div> <div 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